Trospium chloride
Cobenfy, Trospium (trospium chloride) is a small molecule pharmaceutical. Trospium chloride was first approved as Sanctura on 2004-05-28. It is used to treat overactive urinary bladder and urge urinary incontinence in the USA.
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Events Timeline
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| urogenital diseases | D000091642 |
| signs and symptoms pathological conditions | D013568 |
Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cobenfy | New Drug Application | 2024-09-30 |
| trospium chloride | ANDA | 2025-02-13 |
Indications
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Drug
General
| Drug common name | Trospium chloride |
| INN | trospium chloride |
| Description | Trospium chloride is a muscarinic antagonist used to treat overactive bladder. It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed. However it doesn't cause central nervous system side effects like some other muscarinic antagonists. It is in pregnancy category C and is excreted in breast milk.
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| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O[C@@H]1C[C@@H]2CC[C@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-] |
Identifiers
| PDB | — |
| CAS-ID | 10405-02-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3084748 |
| ChEBI ID | — |
| PubChem CID | 107979 |
| DrugBank | DBSALT000883 |
| UNII ID | 1E6682427E (ChemIDplus, GSRS) |
Target
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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